Smoking, alcohol consumption, and frailty: A Mendelian randomization study

Smoking, alcohol consumption, and frailty: A Mendelian randomization study

Background: Tobacco smoking and alcohol consumption have been associated with frailty in observational studies. We sought to examine whether these associations reflect causality using the two-sample Mendelian randomization (MR) design.Methods: We used summary genome-wide association statistics for s...

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Bibliographic Details
Main Authors: Jiannan Lv, Lianghua Wu, Sheng Sun, Huifang Yu, Zekai Shen, Jun Xu, Jiahao Zhu, Dingwan Chen, Minmin Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Genetics
Subjects:
smoking
alcohol
frailty
Mendelian randomization
causality
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1092410/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2023.1092410/full

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