Beclin1 haploinsufficiency compromises mesenchymal stem cell-offered cardioprotection against myocardial infarction

Beclin1 haploinsufficiency compromises mesenchymal stem cell-offered cardioprotection against myocardial infarction

Abstract Mesenchymal stem cells (MSCs)-based therapy has displayed some promises in ischemia heart diseases although its efficacy may be affected by changes in surrounding environments. This study evaluated the role of autophagy insufficiency using Beclin1 haploinsufficiency (BECN+/−) on intra-myoca...

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Bibliographic Details
Main Authors: Xing Qin, Juanjuan Fei, Yu Duan, Asli F. Ceylan, Fuyang Zhang, Jun Ren
Format: Article
Language:English
Published: SpringerOpen 2022-06-01
Series:Cell Regeneration
Subjects:
Myocardial infarction
MSCs
Beclin1
Contraction
Apoptosis
Autophagy
Online Access:https://doi.org/10.1186/s13619-022-00121-y

Internet

https://doi.org/10.1186/s13619-022-00121-y

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