Hydroxide-Mediated S<sub>N</sub>Ar Rearrangement for Synthesis of Novel Depside Derivatives Containing Diaryl Ether Skeleton as Antitumor Agents

Hydroxide-Mediated S<sub>N</sub>Ar Rearrangement for Synthesis of Novel Depside Derivatives Containing Diaryl Ether Skeleton as Antitumor Agents

A simple and efficient hydroxide-mediated S<sub>N</sub>Ar rearrangement was reported to synthesize new depside derivatives containing the diaryl ether skeleton from the natural product barbatic acid. The prepared compounds were determined using <sup>1</sup>H NMR, <sup>1...

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Bibliographic Details
Main Authors: Xiang Yu, Yinkai Xi, Yi Sui, Yang Liu, Guifen Chen, Minjie Zhang, Yan Zhang, Guoyong Luo, Yi Long, Wude Yang
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Molecules
Subjects:
barbatic acid
diaryl ethers
S<sub>N</sub>Ar rearrangement
antitumor activity
Online Access:https://www.mdpi.com/1420-3049/28/11/4303

Internet

https://www.mdpi.com/1420-3049/28/11/4303

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