Salmonella enterica serovar Typhi plasmid pRST98 enhances intracellular bacterial growth and S. typhi-induced macrophage cell death by suppressing autophagy

Objectives: Plasmid pRST98 is a hybrid resistance-virulence plasmid isolated from Salmonella enterica serovar Typhi (S. typhi). Previous studies demonstrated that pRST98 could enhance the virulence of its host bacteria. However, the mechanism of pRST98-increased bacterial virulence is still not full...

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Bibliographic Details
Main Authors: Peiyan He, Shuyan Wu, Yuanyuan Chu, Yanru Yang, Yuanyuan Li, Rui Huang
Format: Article
Language:English
Published: Elsevier 2012-05-01
Series:Brazilian Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S1413867012703215