Evaluation of the effect of reduced-dose pneumococcal conjugate vaccine schedules on vaccine serotype carriage in children and their caretakers in a naïve population in Vietnam: Protocol for a cluster randomized non-inferiority trial [version 1; peer review: 2 approved, 1 approved with reservations]

Introduction: The WHO currently recommends giving pneumococcal conjugate vaccines (PCVs) as three doses – either three doses in infancy with Pentavalent vaccine (3p+0), or two doses in infancy followed by a booster around 12 months (2p+1). However, their high price is a barrier to introduction and s...

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Bibliographic Details
Main Authors: Lay-Myint Yoshida, Kim Mulholland, Stefan Flasche, Cattram Nguyen, Hien-Anh Nguyen, Duc-Anh Dang, Michiko Toizumi
Format: Article
Language:English
Published: F1000 Research Ltd 2023-07-01
Series:Gates Open Research
Subjects:
Online Access:https://gatesopenresearch.org/articles/7-110/v1