Cell Surface Fibroblast Activation Protein-2 (Fap2) of <i>Fusobacterium nucleatum</i> as a Vaccine Candidate for Therapeutic Intervention of Human Colorectal Cancer: An Immunoinformatics Approach

Cell Surface Fibroblast Activation Protein-2 (Fap2) of <i>Fusobacterium nucleatum</i> as a Vaccine Candidate for Therapeutic Intervention of Human Colorectal Cancer: An Immunoinformatics Approach

Colorectal cancer (CRC) is one of the most common cancers and is the second-highest in cancer-related deaths worldwide. The changes in gut homeostasis and microbial dysbiosis lead to the initiation of the tumorigenesis process. Several pathogenic gram-negative bacteria including <i>Fusobacteri...

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Bibliographic Details
Main Authors: Somrita Padma, Ritwik Patra, Parth Sarthi Sen Gupta, Saroj Kumar Panda, Malay Kumar Rana, Suprabhat Mukherjee
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Vaccines
Subjects:
human colorectal cancer
<i>Fusobacterium nucleatum</i>
fibroblast activation protein-2 (Fap2)
toll-like receptors (TLRs)
multi-epitope peptide vaccine
cloning
Online Access:https://www.mdpi.com/2076-393X/11/3/525

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https://www.mdpi.com/2076-393X/11/3/525

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