Decanoyl-Arg-Val-Lys-Arg-Chloromethylketone: An Antiviral Compound That Acts against Flaviviruses through the Inhibition of Furin-Mediated prM Cleavage

Decanoyl-Arg-Val-Lys-Arg-Chloromethylketone: An Antiviral Compound That Acts against Flaviviruses through the Inhibition of Furin-Mediated prM Cleavage

Flaviviruses, such as Zika virus (ZIKV), Japanese encephalitis virus (JEV), Dengue virus (DENV), and West Nile virus (WNV), are important arthropod-borne pathogens that present an immense global health problem. Their unpredictable disease severity, unusual clinical features, and severe neurological...

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Bibliographic Details
Main Authors: Muhammad Imran, Muhammad Kashif Saleemi, Zheng Chen, Xugang Wang, Dengyuan Zhou, Yunchuan Li, Zikai Zhao, Bohan Zheng, Qiuyan Li, Shengbo Cao, Jing Ye
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Viruses
Subjects:
flavivirus
zika virus
japanese encephalitis virus
furin inhibitor
precursor membrane protein
Online Access:https://www.mdpi.com/1999-4915/11/11/1011

Internet

https://www.mdpi.com/1999-4915/11/11/1011

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