Functional Dissection of the Nascent Polypeptide-Associated Complex in Saccharomyces cerevisiae.

Both the yeast nascent polypeptide-associated complex (NAC) and the Hsp40/70-based chaperone system RAC-Ssb are systems tethered to the ribosome to assist cotranslational processes such as folding of nascent polypeptides. While loss of NAC does not cause phenotypic changes in yeast, the simultaneous...

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Bibliographic Details
Main Authors: Ann-Kathrin Ott, Lisa Locher, Miriam Koch, Elke Deuerling
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4664479?pdf=render