Mutational analysis of the spike protein of SARS-COV-2 isolates revealed atomistic features responsible for higher binding and infectivity

Mutational analysis of the spike protein of SARS-COV-2 isolates revealed atomistic features responsible for higher binding and infectivity

Introduction: The perpetual appearance of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2), and its new variants devastated the public health and social fabric around the world. Understanding the genomic patterns and connecting them to phenotypic attributes is of great interest to devise...

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Bibliographic Details
Main Authors: Muhammad Hanifa, Muhammad Salman, Muqaddas Fatima, Naila Mukhtar, Fahad N. Almajhdi, Nasib Zaman, Muhammad Suleman, Syed Shujait Ali, Yasir Waheed, Abbas Khan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
SARS-CoV-2
variants
genomes
spike protein
docking
simulation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.940863/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.940863/full

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