Vitamin A deficiency and vitamin A supplementation affect innate and T cell immune responses to rotavirus A infection in a conventional sow model

Vitamin A deficiency and vitamin A supplementation affect innate and T cell immune responses to rotavirus A infection in a conventional sow model

Rotavirus A (RVA) causes ~200,000 diarrheal deaths annually in children <5yrs, mostly in low- and middle-income countries. Risk factors include nutritional status, social factors, breastfeeding status, and immunodeficiency. We evaluated the effects of vitamin A (VA) deficiency/VA supplementat...

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Bibliographic Details
Main Authors: Juliet Chepngeno, Joshua O. Amimo, Husheem Michael, Sergei A. Raev, Kwonil Jung, Marcia V. Lee, Debasu Damtie, Alfred Omwando, Anastasia N. Vlasova, Linda J. Saif
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
Subjects:
Rotavirus A
innate immune responses
dendritic cells
natural killer cells
T cells
sow model
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1188757/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1188757/full

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