Distinct and Dynamic Changes in the Temporal Profiles of Neurotransmitters in <i>Drosophila melanogaster</i> Brain following Volatilized Cocaine or Methamphetamine Administrations

Distinct and Dynamic Changes in the Temporal Profiles of Neurotransmitters in <i>Drosophila melanogaster</i> Brain following Volatilized Cocaine or Methamphetamine Administrations

Due to similarities in genetics, cellular response, and behavior, <i>Drosophila</i> is used as a model organism in addiction research. A well-described behavioral response examined in flies is the induced increase in locomotor activity after a single dose of volatilized cocaine (vCOC) an...

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Bibliographic Details
Main Authors: Ana Filošević Vujnović, Lara Saftić Martinović, Marta Medija, Rozi Andretić Waldowski
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Pharmaceuticals
Subjects:
<i>Drosophila melanogaster</i>
cocaine
methamphetamine
neurotransmitter concentration
locomotor sensitization
LC-MS/MS
Online Access:https://www.mdpi.com/1424-8247/16/10/1489

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https://www.mdpi.com/1424-8247/16/10/1489

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