Molecular profiling of male breast cancer by multigene panel testing: Implications for precision oncology

Molecular profiling of male breast cancer by multigene panel testing: Implications for precision oncology

IntroductionCompared with breast cancer (BC) in women, BC in men is a rare disease with genetic and molecular peculiarities. Therapeutic approaches for male BC (MBC) are currently extrapolated from the clinical management of female BC, although the disease does not exactly overlap in males and femal...

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Bibliographic Details
Main Authors: Virginia Valentini, Valentina Silvestri, Agostino Bucalo, Giulia Conti, Mina Karimi, Linda Di Francesco, Giulia Pomati, Silvia Mezi, Bruna Cerbelli, Maria Gemma Pignataro, Arianna Nicolussi, Anna Coppa, Giulia D’Amati, Giuseppe Giannini, Laura Ottini
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Oncology
Subjects:
male breast cancer (MBC)
tumor profiling
targeted gene panel sequencing
clinically actionable genetic variants
tumor mutational burden (TMB)
microsatellite instability (MSI)
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1092201/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.1092201/full

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