JNK controls the onset of mitosis in planarian stem cells and triggers apoptotic cell death required for regeneration and remodeling.

Regeneration of lost tissues depends on the precise interpretation of molecular signals that control and coordinate the onset of proliferation, cellular differentiation and cell death. However, the nature of those molecular signals and the mechanisms that integrate the cellular responses remain larg...

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Bibliographic Details
Main Authors: María Almuedo-Castillo, Xenia Crespo-Yanez, Florian Seebeck, Kerstin Bartscherer, Emili Salò, Teresa Adell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4055413?pdf=render