LncRNA XIST from the bone marrow mesenchymal stem cell derived exosome promotes osteosarcoma growth and metastasis through miR-655/ACLY signal

LncRNA XIST from the bone marrow mesenchymal stem cell derived exosome promotes osteosarcoma growth and metastasis through miR-655/ACLY signal

Abstract Background Long non-coding RNA X-inactive specific transcript (XIST) regulates the progression of a variety of tumors, including osteosarcoma. Bone marrow mesenchymal stem cells (BMSCs) can be recruited into osteosarcoma tissue and affect the progression by secreting exosomes. However, whet...

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Bibliographic Details
Main Authors: Guanghui Zhu, Yu Xia, Ziyue Zhao, Aoyu Li, Hui Li, Tao Xiao
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Cancer Cell International
Subjects:
Bone marrow mesenchymal stem cells
Osteosarcoma
Exosome
LncRNA XIST
miR-655
Online Access:https://doi.org/10.1186/s12935-022-02746-0

Internet

https://doi.org/10.1186/s12935-022-02746-0

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