Development of an ELISA-Based Potency Assay for Inactivated Influenza Vaccines Using Cross-Reactive Nanobodies

Development of an ELISA-Based Potency Assay for Inactivated Influenza Vaccines Using Cross-Reactive Nanobodies

Inactivated vaccines are the main influenza vaccines used today; these are usually presented as split (detergent-disrupted) or subunit vaccines, while whole-virus-inactivated influenza vaccines are rare. The single radial immune diffusion (SRD) assay has been used as the gold standard potency assay...

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Bibliographic Details
Main Authors: Chung Y. Cheung, Sitara Dubey, Martina Hadrovic, Christina R. Ball, Walter Ramage, Jacqueline U. McDonald, Ruth Harvey, Simon E. Hufton, Othmar G. Engelhardt
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Vaccines
Subjects:
influenza
vaccine
potency test
nanobodies
ELISA
cross-reactive
Online Access:https://www.mdpi.com/2076-393X/10/9/1473

Internet

https://www.mdpi.com/2076-393X/10/9/1473

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