Deciphering the Rules Underlying Xenogeneic Silencing and Counter-Silencing of Lsr2-like Proteins Using CgpS of <named-content content-type="genus-species">Corynebacterium glutamicum</named-content> as a Model

Deciphering the Rules Underlying Xenogeneic Silencing and Counter-Silencing of Lsr2-like Proteins Using CgpS of <named-content content-type="genus-species">Corynebacterium glutamicum</named-content> as a Model

ABSTRACT Lsr2-like nucleoid-associated proteins play an important role as xenogeneic silencers (XS) of horizontally acquired genomic regions in actinobacteria. In this study, we systematically analyzed the in vivo constraints underlying silencing and counter-silencing of the Lsr2-like protein CgpS i...

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Bibliographic Details
Main Authors: Johanna Wiechert, Andrei Filipchyk, Max Hünnefeld, Cornelia Gätgens, Jannis Brehm, Ralf Heermann, Julia Frunzke
Format: Article
Language:English
Published: American Society for Microbiology 2020-02-01
Series:mBio
Subjects:
AT-rich DNA
Lsr2
actinobacteria
counter-silencing
horizontal gene transfer
regulatory networks
Online Access:https://journals.asm.org/doi/10.1128/mBio.02273-19

Internet

https://journals.asm.org/doi/10.1128/mBio.02273-19

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