Growth Inhibition of MDA-MB-231 Cell Line by Peptides Designed based on uPA

Interaction between urokinase-type plasminogen activator (uPA) and its receptor (uPAR) plays an important role in the progression of numerous cancer types including breast cancer by promoting tumor initiating,  proliferation,  invasion  and  metastasis.  Hence,  disruption  of  this  interaction  in...

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Bibliographic Details
Main Authors: Parastoo Tarighi, Mohammad Reza Khorramizadeh, Armin Madadkar Sobhani, Seyed Nasser Ostad, Mohammad Hossein Ghahremani
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2015-10-01
Series:Acta Medica Iranica
Subjects:
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/4270