Effect of dietary inflammatory potential on the aging acceleration for cardiometabolic disease: A population-based study
Background/AimOptimized dietary patterns have been considered an important determinant of delaying aging in cardiometabolic disease (CMD). Dietary pattern with high-level dietary inflammatory potential is a key risk factor for cardiometabolic disease, and has drawn increasing attention. The aim of t...
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| Language: | English |
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Frontiers Media S.A.
2022-12-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2022.1048448/full |
| _version_ | 1828097572746559488 |
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| author | Yuanlong Hu Yuanlong Hu Xiaojie Wang Xiaojie Wang Jiaming Huan Lei Zhang Lei Zhang Lin Lin Lin Lin Yuan Li Yuan Li Yuan Li Yunlun Li Yunlun Li Yunlun Li |
| author_facet | Yuanlong Hu Yuanlong Hu Xiaojie Wang Xiaojie Wang Jiaming Huan Lei Zhang Lei Zhang Lin Lin Lin Lin Yuan Li Yuan Li Yuan Li Yunlun Li Yunlun Li Yunlun Li |
| author_sort | Yuanlong Hu |
| collection | DOAJ |
| description | Background/AimOptimized dietary patterns have been considered an important determinant of delaying aging in cardiometabolic disease (CMD). Dietary pattern with high-level dietary inflammatory potential is a key risk factor for cardiometabolic disease, and has drawn increasing attention. The aim of this study was to investigate whether dietary pattern with high dietary inflammatory potential was associated with aging acceleration in cardiometabolic disease.Materials and methodsWe analyzed the cross-sectional data from six survey cycles (1999–2000, 2001–2002, 2003–2004, 2005–2006, 2007–2008, and 2009–2010) of the National Health and Nutritional Examination Surveys (NHANES). A total of 16,681 non-institutionalized adults and non-pregnant females with CMD were included in this study. Dietary inflammatory index (DII) was used to assess the dietary inflammatory potential. The two age acceleration biomarkers were calculated by the residuals from regressing chronologic age on Klemera-Doubal method biological age (KDM BioAge) or Phenotypic Age (PhenoAge), termed “KDMAccel” and “PhenoAgeAccel.” A multivariable linear regression accounting for multistage survey design and sampling weights was used in different models to investigate the association between DII and aging acceleration. Four sensitivity analyses were used to ensure the robustness of our results. Besides, we also analyzed the anti-aging effects of DASH-type dietary pattern and “Life’s Simple 7”.ResultsFor 16,681 participants with CMD, compared with the first tertile of DII after adjusting for all potential confounders, the patients with second tertile of DII showed a 1.02-years increase in KDMAccel and 0.63-years increase in PhenoAgeAccel (KDMAccel, β = 1.02, 95% CI = 0.64 to 1.41, P < 0.001; PhenoAgeAccel, β = 0.63, 95% CI = 0.44 to 0.82, P < 0.001), while the patients with the third tertile of DII showed a 1.48-years increase in KDMAccel and 1.22-years increase in PhenoAgeAccel (KDMAccel, β = 1.48, 95% CI = 1.02 to 1.94, P < 0.001; PhenoAgeAccel, β = 1.22, 95% CI = 1.01 to 1.43, P < 0.001). In addition, DASH-type dietary pattern was associated with a 0.57-years reduction in KDMAccel (β = −0.57, 95% CI = −1.08 to −0.06, P = 0.031) and a 0.54-years reduction in PhenoAgeAccel (β = −0.54, 95% CI = −0.80 to −0.28, P < 0.001). The each one-unit increase in CVH score was associated with a 1.58-years decrease in KDMAccel (β = −1.58, 95% CI = −1.68 to −1.49, P < 0.001) and a 0.36-years in PhenoAgeAccel (β = −0.36, 95% CI = −0.41 to −0.31, P < 0.001).ConclusionAmong CMD, the dietary pattern with high dietary inflammatory potential was association with aging acceleration, and the anti-aging potential of DASH-type dietary pattern and “Life’s Simple 7” should also be given attention, but these observations require future prospective validation. |
| first_indexed | 2024-04-11T07:48:05Z |
| format | Article |
| id | doaj.art-30cdf6eb639d403f86a73f7351bdcbb8 |
| institution | Directory Open Access Journal |
| issn | 2296-861X |
| language | English |
| last_indexed | 2024-04-11T07:48:05Z |
| publishDate | 2022-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj.art-30cdf6eb639d403f86a73f7351bdcbb82022-12-22T04:36:10ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2022-12-01910.3389/fnut.2022.10484481048448Effect of dietary inflammatory potential on the aging acceleration for cardiometabolic disease: A population-based studyYuanlong Hu0Yuanlong Hu1Xiaojie Wang2Xiaojie Wang3Jiaming Huan4Lei Zhang5Lei Zhang6Lin Lin7Lin Lin8Yuan Li9Yuan Li10Yuan Li11Yunlun Li12Yunlun Li13Yunlun Li14First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, ChinaShandong Province Engineering Laboratory of Traditional Chinese Medicine Precise Diagnosis and Treatment of Cardiovascular Disease, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, ChinaShandong Province Engineering Laboratory of Traditional Chinese Medicine Precise Diagnosis and Treatment of Cardiovascular Disease, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, ChinaFaculty of Chinese Medicine, Macau University of Science and Technology, Taipa, Macau, ChinaCollege of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, ChinaShandong Province Engineering Laboratory of Traditional Chinese Medicine Precise Diagnosis and Treatment of Cardiovascular Disease, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, ChinaCollege of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, ChinaShandong Province Engineering Laboratory of Traditional Chinese Medicine Precise Diagnosis and Treatment of Cardiovascular Disease, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, ChinaInnovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, ChinaExperimental Center, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, ChinaKey Laboratory of Traditional Chinese Medicine Classical Theory, Ministry of Education, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, ChinaShandong Provincial Key Laboratory of Traditional Chinese Medicine for Basic Research, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, ChinaFirst Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, ChinaShandong Province Engineering Laboratory of Traditional Chinese Medicine Precise Diagnosis and Treatment of Cardiovascular Disease, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, ChinaDepartment of Cardiovascular, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, ChinaBackground/AimOptimized dietary patterns have been considered an important determinant of delaying aging in cardiometabolic disease (CMD). Dietary pattern with high-level dietary inflammatory potential is a key risk factor for cardiometabolic disease, and has drawn increasing attention. The aim of this study was to investigate whether dietary pattern with high dietary inflammatory potential was associated with aging acceleration in cardiometabolic disease.Materials and methodsWe analyzed the cross-sectional data from six survey cycles (1999–2000, 2001–2002, 2003–2004, 2005–2006, 2007–2008, and 2009–2010) of the National Health and Nutritional Examination Surveys (NHANES). A total of 16,681 non-institutionalized adults and non-pregnant females with CMD were included in this study. Dietary inflammatory index (DII) was used to assess the dietary inflammatory potential. The two age acceleration biomarkers were calculated by the residuals from regressing chronologic age on Klemera-Doubal method biological age (KDM BioAge) or Phenotypic Age (PhenoAge), termed “KDMAccel” and “PhenoAgeAccel.” A multivariable linear regression accounting for multistage survey design and sampling weights was used in different models to investigate the association between DII and aging acceleration. Four sensitivity analyses were used to ensure the robustness of our results. Besides, we also analyzed the anti-aging effects of DASH-type dietary pattern and “Life’s Simple 7”.ResultsFor 16,681 participants with CMD, compared with the first tertile of DII after adjusting for all potential confounders, the patients with second tertile of DII showed a 1.02-years increase in KDMAccel and 0.63-years increase in PhenoAgeAccel (KDMAccel, β = 1.02, 95% CI = 0.64 to 1.41, P < 0.001; PhenoAgeAccel, β = 0.63, 95% CI = 0.44 to 0.82, P < 0.001), while the patients with the third tertile of DII showed a 1.48-years increase in KDMAccel and 1.22-years increase in PhenoAgeAccel (KDMAccel, β = 1.48, 95% CI = 1.02 to 1.94, P < 0.001; PhenoAgeAccel, β = 1.22, 95% CI = 1.01 to 1.43, P < 0.001). In addition, DASH-type dietary pattern was associated with a 0.57-years reduction in KDMAccel (β = −0.57, 95% CI = −1.08 to −0.06, P = 0.031) and a 0.54-years reduction in PhenoAgeAccel (β = −0.54, 95% CI = −0.80 to −0.28, P < 0.001). The each one-unit increase in CVH score was associated with a 1.58-years decrease in KDMAccel (β = −1.58, 95% CI = −1.68 to −1.49, P < 0.001) and a 0.36-years in PhenoAgeAccel (β = −0.36, 95% CI = −0.41 to −0.31, P < 0.001).ConclusionAmong CMD, the dietary pattern with high dietary inflammatory potential was association with aging acceleration, and the anti-aging potential of DASH-type dietary pattern and “Life’s Simple 7” should also be given attention, but these observations require future prospective validation.https://www.frontiersin.org/articles/10.3389/fnut.2022.1048448/fulldietary inflammatory potentialdietary inflammatory indexaging accelerationbiological agingcardiometabolic disease |
| spellingShingle | Yuanlong Hu Yuanlong Hu Xiaojie Wang Xiaojie Wang Jiaming Huan Lei Zhang Lei Zhang Lin Lin Lin Lin Yuan Li Yuan Li Yuan Li Yunlun Li Yunlun Li Yunlun Li Effect of dietary inflammatory potential on the aging acceleration for cardiometabolic disease: A population-based study Frontiers in Nutrition dietary inflammatory potential dietary inflammatory index aging acceleration biological aging cardiometabolic disease |
| title | Effect of dietary inflammatory potential on the aging acceleration for cardiometabolic disease: A population-based study |
| title_full | Effect of dietary inflammatory potential on the aging acceleration for cardiometabolic disease: A population-based study |
| title_fullStr | Effect of dietary inflammatory potential on the aging acceleration for cardiometabolic disease: A population-based study |
| title_full_unstemmed | Effect of dietary inflammatory potential on the aging acceleration for cardiometabolic disease: A population-based study |
| title_short | Effect of dietary inflammatory potential on the aging acceleration for cardiometabolic disease: A population-based study |
| title_sort | effect of dietary inflammatory potential on the aging acceleration for cardiometabolic disease a population based study |
| topic | dietary inflammatory potential dietary inflammatory index aging acceleration biological aging cardiometabolic disease |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2022.1048448/full |
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