Partial Substitution of Glucose with Xylitol Prolongs Survival and Suppresses Cell Proliferation and Glycolysis of Mice Bearing Orthotopic Xenograft of Oral Cancer

Partial Substitution of Glucose with Xylitol Prolongs Survival and Suppresses Cell Proliferation and Glycolysis of Mice Bearing Orthotopic Xenograft of Oral Cancer

Many types of cancer have metabolic alterations with increased glycolysis. Identification of alternative sweeteners that do not fuel cancer is a novel approach to cancer control. The present study aimed to investigate the effects of xylitol on tumor growth and survival of mice bearing orthotopic xen...

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Bibliographic Details
Main Authors: Yuraporn Sahasakul, Wannee Angkhasirisap, Aroonwan Lam-ubol, Amornrat Aursalung, Daisuke Sano, Kentaro Takada, Dunyaporn Trachootham
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Nutrients
Subjects:
oral cancer
orthotopic xenograft model
xylitol
glucose
glycolysis
sweetener
Online Access:https://www.mdpi.com/2072-6643/14/10/2023

Internet

https://www.mdpi.com/2072-6643/14/10/2023

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