Two apicoplast dwelling glycolytic enzymes provide key substrates for metabolic pathways in the apicoplast and are critical for Toxoplasma growth.

Many apicomplexan parasites harbor a non-photosynthetic plastid called the apicoplast, which hosts important metabolic pathways like the methylerythritol 4-phosphate (MEP) pathway that synthesizes isoprenoid precursors. Yet many details in apicoplast metabolism are not well understood. In this study...

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Bibliographic Details
Main Authors: Zhipeng Niu, Shu Ye, Jiaojiao Liu, Mengyu Lyu, Lilan Xue, Muxiao Li, Congcong Lyu, Junlong Zhao, Bang Shen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1011009