Mitochondria Are Dynamically Transferring Between Human Neural Cells and Alexander Disease-Associated GFAP Mutations Impair the Astrocytic Transfer

Mitochondria Are Dynamically Transferring Between Human Neural Cells and Alexander Disease-Associated GFAP Mutations Impair the Astrocytic Transfer

Mitochondria are the critical organelles for energy metabolism and cell survival in eukaryotic cells. Recent studies demonstrated that mitochondria can intercellularly transfer between mammalian cells. In neural cells, astrocytes transfer mitochondria into neurons in a CD38-dependent manner. Here, u...

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Bibliographic Details
Main Authors: Longfei Gao, Zhen Zhang, Jing Lu, Gang Pei
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
mitochondria
transfer
astrocytes
neuronal cells
GFAP mutation
Alexander disease
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00316/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2019.00316/full

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