Cancer Metastases to Bone: Concepts, Mechanisms, and Interactions with Bone Osteoblasts

Cancer Metastases to Bone: Concepts, Mechanisms, and Interactions with Bone Osteoblasts

The skeleton is a unique structure capable of providing support for the body. Bone resorption and deposition are controlled in a tightly regulated balance between osteoblasts and osteoclasts with no net bone gain or loss. However, under conditions of disease, the balance between bone resorption and...

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Bibliographic Details
Main Authors: Alison B. Shupp, Alexus D. Kolb, Dimpi Mukhopadhyay, Karen M. Bussard
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Cancers
Subjects:
osteoblast
osteoclast
metastasis
breast cancer
prostate cancer
multiple myeloma
bone
dormancy
re-activation
osteomimicry
Online Access:http://www.mdpi.com/2072-6694/10/6/182

Internet

http://www.mdpi.com/2072-6694/10/6/182

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