PIEZO1 ACTIVATION INCREASES NEUTROPHIL ADHESIVE PROPERTIES IN SICKLE CELL ANEMIA

Sickle cell anemia (SCA) is an inherited disorder caused by a mutation in the gene encoding β-globin. This mutation brings about alterations in the hemoglobin molecule, resulting in abnormal red blood cell (RBC) properties, shape, and subsequent destruction in the circulation, leading to anemia and...

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Bibliographic Details
Main Authors: FC Leonardo, PL Brito, S Egée, E Nader, P Connes, STO Saad, FF Costa, N Conran
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Hematology, Transfusion and Cell Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2531137923003395