Chlorotoxin: A Helpful Natural Scorpion Peptide to Diagnose Glioma and Fight Tumor Invasion

Chlorotoxin: A Helpful Natural Scorpion Peptide to Diagnose Glioma and Fight Tumor Invasion

Chlorotoxin is a small 36 amino-acid peptide identified from the venom of the scorpion Leiurus quinquestriatus. Initially, chlorotoxin was used as a pharmacological tool to characterize chloride channels. While studying glioma-specific chloride currents, it was soon discovered that chlorotoxin posse...

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Bibliographic Details
Main Authors: Lucie Dardevet, Dipti Rani, Tarek Abd El Aziz, Ingrid Bazin, Jean-Marc Sabatier, Mahmoud Fadl, Elisabeth Brambilla, Michel De Waard
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Toxins
Subjects:
chlorotoxin
glioma
cancer
targeting
diagnosis
treatment
therapy
chloride channel
Annexin A2
metalloprotease
Online Access:http://www.mdpi.com/2072-6651/7/4/1079

Internet

http://www.mdpi.com/2072-6651/7/4/1079

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