Imaging sensitive and drug-resistant bacterial infection with [11C]-trimethoprim

Imaging sensitive and drug-resistant bacterial infection with [11C]-trimethoprim

BACKGROUND Several molecular imaging strategies can identify bacterial infections in humans. PET affords the potential for sensitive infection detection deep within the body. Among PET-based approaches, antibiotic-based radiotracers, which often target key bacterial-specific enzymes, have considerab...

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Bibliographic Details
Main Authors: Iris K. Lee, Daniel A. Jacome, Joshua K. Cho, Vincent Tu, Anthony J. Young, Tiffany Dominguez, Justin D. Northrup, Jean M. Etersque, Hsiaoju S. Lee, Andrew Ruff, Ouniol Aklilu, Kyle Bittinger, Laurel J. Glaser, Daniel Dorgan, Denis Hadjiliadis, Rahul M. Kohli, Robert H. Mach, David A. Mankoff, Robert K. Doot, Mark A. Sellmyer
Format: Article
Language:English
Published: American Society for Clinical Investigation 2023-03-01
Series:The Journal of Clinical Investigation
Subjects:
Infectious disease
Online Access:https://doi.org/10.1172/JCI156679

Internet

https://doi.org/10.1172/JCI156679

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