MFN2 deficiency affects calcium homeostasis in lung adenocarcinoma cells via downregulation of UCP4

MFN2 deficiency affects calcium homeostasis in lung adenocarcinoma cells via downregulation of UCP4

Mitofusin‐2 (MFN2) is a transmembrane GTPase that regulates mitochondrial fusion and thereby modulates mitochondrial function. However, the role of MFN2 in lung adenocarcinoma remains controversial. Here, we investigated the effect of MFN2 regulation on mitochondria in lung adenocarcinoma. We found...

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Bibliographic Details
Main Authors: Jingjing Zhang, Lifang Pan, Qiang Zhang, Yanyan Zhao, Wenwen Wang, Nengming Lin, Shirong Zhang, Qiong Wu
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:FEBS Open Bio
Subjects:
calcium homeostasis
lung adenocarcinoma
MFN2
UCP4
Online Access:https://doi.org/10.1002/2211-5463.13591

Internet

https://doi.org/10.1002/2211-5463.13591

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