Functions and Mechanisms of Pro-Lysyl Oxidase Processing in Cancers and Eye Pathologies with a Focus on Diabetic Retinopathy

Functions and Mechanisms of Pro-Lysyl Oxidase Processing in Cancers and Eye Pathologies with a Focus on Diabetic Retinopathy

Lysyl oxidases are multifunctional proteins derived from five lysyl oxidase paralogues <i>(LOX)</i> and lysyl oxidase-like 1 through lysyl oxidase-like 4 (<i>LOXL1–LOXL4</i>). All participate in the biosynthesis of and maturation of connective tissues by catalyzing the oxidat...

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Bibliographic Details
Main Authors: Philip C. Trackman, Yaser Peymanfar, Sayon Roy
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
lysyl oxidase
lysyl oxidase propeptide
structure–function
diabetes
eye pathologies
Online Access:https://www.mdpi.com/1422-0067/23/9/5088

Internet

https://www.mdpi.com/1422-0067/23/9/5088

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