Strain-based and sex-biased differences in adrenal and pancreatic gene expression between KK/HlJ and C57BL/6 J mice

Strain-based and sex-biased differences in adrenal and pancreatic gene expression between KK/HlJ and C57BL/6 J mice

Abstract Background The ever-increasing prevalence of diabetes and associated comorbidities serves to highlight the necessity of biologically relevant small-animal models to investigate its etiology, pathology and treatment. Although the C57BL/6 J model is amongst the most widely used mouse model du...

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Bibliographic Details
Main Authors: Angela Inglis, Rosario Ubungen, Sarah Farooq, Princess Mata, Jennifer Thiam, Soad Saleh, Sherin Shibin, Futwan A. Al-Mohanna, Kate S. Collison
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Genomics
Subjects:
Microarray
Strain
Gene expression
Glucose homeostasis
Insulin tolerance test
C57BL/6 J
Online Access:https://doi.org/10.1186/s12864-021-07495-4

Internet

https://doi.org/10.1186/s12864-021-07495-4

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