Urine Phenylacetylglutamine Determination in Patients with Hyperphenylalaninemia

Urine Phenylacetylglutamine Determination in Patients with Hyperphenylalaninemia

Phenylketonuria (PKU), an autosomal-recessive inborn error of phenylalanine (Phe) metabolism is the most prevalent disorder of amino acid metabolism. Currently, clinical follow-up relies on frequent monitoring of Phe levels in blood. We hypothesize that the urine level of phenylacetylglutamine (PAG)...

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Bibliographic Details
Main Authors: Fernando Andrade, Ainara Cano, María Unceta Suarez, Arantza Arza, Ana Vinuesa, Leticia Ceberio, Nuria López-Oslé, Gorka de Frutos, Raquel López-Oceja, Elena Aznal, Domingo González-Lamuño, Javier de las Heras
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Journal of Clinical Medicine
Subjects:
phenylketonuria
phenylalanine
phenylalanine hydroxylase deficiency
phenylacetylglutamine
biomarkers
dried blood spot
Online Access:https://www.mdpi.com/2077-0383/10/16/3674

Internet

https://www.mdpi.com/2077-0383/10/16/3674

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