Complement activation in human prion disease

The central event in the neuropathological process of prion diseases (PrD) is the accumulation of abnormal prion protein accompanied by severe neuronal loss. Despite the infectious nature of these diseases, no prominent immune response has been detected yet. However, recent studies have shown that c...

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Bibliographic Details
Main Authors: Gabor G Kovacs, Philippe Gasque, Thomas Ströbel, Elisabeth Lindeck-Pozza, Michaela Strohschneider, James W Ironside, Herbert Budka, Marin Guentchev
Format: Article
Language:English
Published: Elsevier 2004-02-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996103001748