Iso-Partricin, an Aromatic Analogue of Amphotericin B: How Shining Light on Old Drugs Might Help Create New Ones

Iso-Partricin, an Aromatic Analogue of Amphotericin B: How Shining Light on Old Drugs Might Help Create New Ones

Partricin is a heptaene macrolide antibiotic complex that exhibits exceptional antifungal activity, yet poor selective toxicity, in the pathogen/host system. It consists of two compounds, namely partricin A and B, and both of these molecules incorporate two <i>cis</i>-type bonds within t...

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Bibliographic Details
Main Authors: Paweł Szczeblewski, Justyna Górska, Witold Andrałojć, Patryk Janke, Karolina Wąsik, Tomasz Laskowski
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Antibiotics
Subjects:
partricin
aureofacin
polyene macrolides
photoisomerization
selective toxicity
structural studies
Online Access:https://www.mdpi.com/2079-6382/10/9/1102

Internet

https://www.mdpi.com/2079-6382/10/9/1102

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