Current and Emerging Strategies for Enhancing Antibody Delivery to the Brain

For the treatment of neurological diseases, achieving sufficient exposure to the brain parenchyma is a critical determinant of drug efficacy. The blood–brain barrier (BBB) functions to tightly control the passage of substances between the bloodstream and the central nervous system, and as such poses...

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Bibliographic Details
Main Authors: Rinie Bajracharya, Alayna C. Caruso, Laura J. Vella, Rebecca M. Nisbet
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/13/12/2014