N-terminal peptide fragment constitutes core of amyloid deposition of serum amyloid A: An imaging mass spectrometry study.

N-terminal peptide fragment constitutes core of amyloid deposition of serum amyloid A: An imaging mass spectrometry study.

Serum amyloid A (SAA) is an acute phase protein, which undergoes structural changes and deposits in the extracellular matrix, causing organ damage. Systemic AA amyloidosis is a relatively common amyloid subtype among the more than 30 amyloid subtypes, but the mechanism of amyloid fibril formation re...

Full description

Bibliographic Details
Main Authors: Yukako Shintani-Domoto, Yuki Sugiura, Makiko Ogawa, Eiji Sugiyama, Hiroyuki Abe, Takashi Sakatani, Ryuji Ohashi, Tetsuo Ushiku, Masashi Fukayama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0275993

Internet

https://doi.org/10.1371/journal.pone.0275993

Similar Items