c-Jun NH2-terminal kinase activation is essential for up-regulation of LC3 during ceramide-induced autophagy in human nasopharyngeal carcinoma cells

<p>Abstract</p> <p>Background</p> <p>Autophagy is a dynamic catabolic process characterized by the formation of double membrane vacuoles termed autophagosomes. LC3, a homologue of yeast Atg8, takes part in autophagosome formation, but the exact regulation mechanism of L...

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Bibliographic Details
Main Authors: Guan Zhong, Ma JianGuo, Xia LiangPing, Wang LinLin, Li DanDan, Sun Ting, Feng GongKan, Zhu XiaoFeng
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/9/1/161