Targeted activation of midbrain neurons restores locomotor function in mouse models of parkinsonism
Here, the authors use cell-type specific stimulation of brainstem neurons within the caudal pedunculopontine nucleus to show that activation of excitatory neurons can normalize severe locomotor deficit in mouse models of parkinsonism. The study defines a potential target for neuromodulatory restorat...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-28075-4 |