Preoperative metabolic tumor volume of intrahepatic cholangiocarcinoma measured by 18F-FDG-PET is associated with the KRAS mutation status and prognosis

Preoperative metabolic tumor volume of intrahepatic cholangiocarcinoma measured by 18F-FDG-PET is associated with the KRAS mutation status and prognosis

Abstract Background Surgical resection remains the mainstay of curative treatment for intrahepatic cholangiocarcinoma (ICC). Prognosis after surgery is unsatisfactory despite improvements in treatment and post-operative clinical management. Despite developments in the molecular profiling of ICC, the...

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Bibliographic Details
Main Authors: Yoshinobu Ikeno, Satoru Seo, Keiko Iwaisako, Tomoaki Yoh, Yuji Nakamoto, Hiroaki Fuji, Kojiro Taura, Hideaki Okajima, Toshimi Kaido, Shimon Sakaguchi, Shinji Uemoto
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Journal of Translational Medicine
Subjects:
Intrahepatic cholangiocarcinoma
KRAS mutation
Glucose uptake
GLUT-1
18F-FDG-PET
Online Access:http://link.springer.com/article/10.1186/s12967-018-1475-x

Internet

http://link.springer.com/article/10.1186/s12967-018-1475-x

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