Extracellular matrix degradation pathways and fatty acid metabolism regulate distinct pulmonary vascular cell types in pulmonary arterial hypertension

Pulmonary arterial hypertension describes a group of diseases characterised by raised pulmonary vascular resistance, resulting from vascular remodelling in the pre-capillary resistance arterioles. Left untreated, patients die from right heart failure. Pulmonary vascular remodelling involves all cell...

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Bibliographic Details
Main Authors: Sharon Mumby, F. Perros, C. Hui, B.L. Xu, W. Xu, V Elyasigomari, A. Hautefort, G. Manaud, M. Humbert, K.F. Chung, S.J. Wort, I.M. Adcock
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Pulmonary Circulation
Online Access:https://doi.org/10.1177/2045894021996190