Extracellular matrix degradation pathways and fatty acid metabolism regulate distinct pulmonary vascular cell types in pulmonary arterial hypertension
Pulmonary arterial hypertension describes a group of diseases characterised by raised pulmonary vascular resistance, resulting from vascular remodelling in the pre-capillary resistance arterioles. Left untreated, patients die from right heart failure. Pulmonary vascular remodelling involves all cell...
Main Authors: | Sharon Mumby, F. Perros, C. Hui, B.L. Xu, W. Xu, V Elyasigomari, A. Hautefort, G. Manaud, M. Humbert, K.F. Chung, S.J. Wort, I.M. Adcock |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2021-03-01
|
Series: | Pulmonary Circulation |
Online Access: | https://doi.org/10.1177/2045894021996190 |
Similar Items
-
Differential responses of pulmonary vascular cells from PAH patients and controls to TNFα and the effect of the BET inhibitor JQ1
by: Sharon Mumby, et al.
Published: (2023-07-01) -
Pulmonary capillary haemangiomatosis: a distinct entity?
by: Jason Weatherald, et al.
Published: (2020-05-01) -
Nuclear factor κ-B is activated in the pulmonary vessels of patients with end-stage idiopathic pulmonary arterial hypertension.
by: Laura C Price, et al.
Published: (2013-01-01) -
Trichloroethylene increases pulmonary endothelial permeability: implication for pulmonary veno-occlusive disease
by: Julien Caliez, et al.
Published: (2020-10-01) -
Smouldering fire or conflagration? An illustrated update on the concept of inflammation in pulmonary arterial hypertension
by: Frédéric Perros, et al.
Published: (2021-12-01)