Temporal requirements of the fragile X mental retardation protein in modulating circadian clock circuit synaptic architecture

Loss of fragile X mental retardation 1 (FMR1) gene function is the most common cause of inherited mental retardation and autism spectrum disorders, characterized by attention disorder, hyperactivity and disruption of circadian activity cycles. Pursuit of effective intervention strategies requires de...

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Bibliographic Details
Main Authors: Cheryl L Gatto, Kendal Broadie
Format: Article
Language:English
Published: Frontiers Media S.A. 2009-08-01
Series:Frontiers in Neural Circuits
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/neuro.04.008.2009/full