Evolution of our understanding of myeloid regulatory cells: from MDSCs to Mregs

The term Myeloid-Derived Suppressor Cells (MDSCs) was first suggested in 2007 in order to reflect on the origin and function of myeloid cells during immunosuppression in cancer and other pathologic conditions. Emerging evidence suggest that MDSCs suppress CTL and Th1 responses in malignant diseases...

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Bibliographic Details
Main Authors: Masoud H Manjili, Xiang-Yang eWang, Scott eAbrams
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00303/full