WRN loss induces switching of telomerase-independent mechanisms of telomere elongation.

Telomere maintenance can occur in the presence of telomerase or in its absence, termed alternative lengthening of telomeres (ALT). ALT adds telomere repeats using recombination-based processes and DNA repair proteins that function in homologous recombination. Our previous work reported that the RecQ...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: April Renee Sandy Gocha, Samir Acharya, Joanna Groden
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: Public Library of Science (PLoS) 2014-01-01
Cyfres:PLoS ONE
Mynediad Ar-lein:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0093991&type=printable