WRN loss induces switching of telomerase-independent mechanisms of telomere elongation.

WRN loss induces switching of telomerase-independent mechanisms of telomere elongation.

Telomere maintenance can occur in the presence of telomerase or in its absence, termed alternative lengthening of telomeres (ALT). ALT adds telomere repeats using recombination-based processes and DNA repair proteins that function in homologous recombination. Our previous work reported that the RecQ...

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Bibliographic Details
Main Authors: April Renee Sandy Gocha, Samir Acharya, Joanna Groden
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0093991&type=printable

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