Establishment of three human induced pluripotent stem cell lines from a type 1 diabetic family harboring sequence variants associated with autoimmunity

Establishment of three human induced pluripotent stem cell lines from a type 1 diabetic family harboring sequence variants associated with autoimmunity

Type 1 diabetes (T1D) is characterized by the autoimmune destruction of insulin-producing β cells. Genetic studies have identified > 60 T1D risk loci that harbor genes with disease-causative alleles. However, determining the biological effects of such loci is often difficult due to limited tissue...

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Bibliographic Details
Main Authors: Edward Po-Fan Chu, Chia-Hung Lin, Candy Hsin-Hua Cho, I-Fen Cheng, Tzu-Chien Kuo, Ruei-Ying Chen, Chia-Nan Liao, Jen-Chien Cheng, Jason Isheng Tsai, Po-Chuan Wang, Shing-Jyh Chang, Chia-Ning Shen
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506120303305

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http://www.sciencedirect.com/science/article/pii/S1873506120303305

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