Chronic in utero mitral inflow obstruction unloads left ventricular volume in a novel late gestation fetal lamb modelCentral MessagePerspective
Objective: The in utero no flow/no grow hypothesis postulates that reduced inflow of blood into the left ventricle due to a stenotic mitral valve could lead to ventricular hypoplasia and hypoplastic left heart syndrome. This has been demonstrated in chick embryos, but less so in large animals. We in...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-12-01
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Series: | JTCVS Open |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666273623003091 |