Dimethyloxalylglycine pretreatment of living donor alleviates both donor and graft liver ischemia-reperfusion injury in rats

Dimethyloxalylglycine pretreatment of living donor alleviates both donor and graft liver ischemia-reperfusion injury in rats

Background: Under the circumstance of the increasing waiting list for liver transplantation, living donor liver transplantation (LDLT) can alleviate the shortage of liver donors to some extent. However, how to reduce both donor and graft ischemia-reperfusion injury (IRI) is still an unsolved problem...

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Bibliographic Details
Main Authors: Degong Jia, Minjie Zhao, Jiefu Luo, Shengwei Li, Jianping Gong, Mingxiang Cheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Pharmacology
Subjects:
living donor liver transplantation
hypoxia-induced transcription factor 1
ischemia-reperfusion injury
dimethyloxalylglycine
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1341575/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1341575/full

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