Age-Related Alterations in Macrophage Distribution and Function Are Associated With Delayed Cutaneous Wound Healing

Age-Related Alterations in Macrophage Distribution and Function Are Associated With Delayed Cutaneous Wound Healing

Ageing-related delays and dysregulated inflammation in wound healing are well-documented in both human and animal models. However, cellular and molecular changes underlying this impairment in healing progression are not fully understood. In this study, we characterised ageing-associated changes to m...

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Bibliographic Details
Main Authors: Christabel Thembela Dube, Yasmin Hui Binn Ong, Kelly Wemyss, Siddharth Krishnan, Tiak Ju Tan, Baptiste Janela, John R. Grainger, Matthew Ronshaugen, Kimberly A. Mace, Chin Yan Lim
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
macrophages
inflammation
wound healing
myeloid cells
proliferation
ageing skin
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.943159/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.943159/full

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