Defective mesenchymal Bmpr1a-mediated BMP signaling causes congenital pulmonary cysts

Defective mesenchymal Bmpr1a-mediated BMP signaling causes congenital pulmonary cysts

Abnormal lung development can cause congenital pulmonary cysts, the mechanisms of which remain largely unknown. Although the cystic lesions are believed to result directly from disrupted airway epithelial cell growth, the extent to which developmental defects in lung mesenchymal cells contribute to...

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Bibliographic Details
Main Authors: Yongfeng Luo, Ke Cao, Joanne Chiu, Hui Chen, Hong-Jun Wang, Matthew E Thornton, Brendan H Grubbs, Martin Kolb, Michael S Parmacek, Yuji Mishina, Wei Shi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-06-01
Series:eLife
Subjects:
BMP signaling
lung mesenchymal cells
pulmonary cysts
lung development
Bmpr1a
airway smooth muscle cells
Online Access:https://elifesciences.org/articles/91876

Internet

https://elifesciences.org/articles/91876

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