Whole-Exome Sequencing of Germline Variants in Non-<i>BRCA</i> Families with Hereditary Breast Cancer

Breast cancer is the most prevalent malignancy among women worldwide and hereditary breast cancer (HBC) accounts for about 5–10% of the cases. Today, the most recurrent genes known are <i>BRCA1</i> and <i>BRCA2</i>, accounting for around 25% of familial cases. Although thousa...

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Main Authors: Yaxuan Liu, Hafdis T. Helgadottir, Pedram Kharaziha, Jungmin Choi, Francesc López-Giráldez, Shrikant M. Mane, Veronica Höiom, Carl Christofer Juhlin, Catharina Larsson, Svetlana Bajalica-Lagercrantz
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Biomedicines
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Online Access:https://www.mdpi.com/2227-9059/10/5/1004