Animal models to investigate the effects of inflammation on remyelination in multiple sclerosis

Multiple sclerosis (MS) is a chronic inflammatory, demyelinating, and neurodegenerative disease of the central nervous system (CNS). In people with MS, impaired remyelination and axonal loss lead to debilitating long-term neurologic deficits. Current MS disease-modifying drugs mainly target peripher...

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Bibliographic Details
Main Authors: Marjan Gharagozloo, Jackson W. Mace, Peter A. Calabresi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.995477/full