Assessment of the physical dependence potential of difelikefalin: Randomized placebo‐controlled study in patients receiving hemodialysis

Abstract Difelikefalin is a selective kappa opioid receptor agonist approved for treating moderate‐to‐severe pruritus in adults undergoing hemodialysis (HD). Difelikefalin is not a controlled substance under the Controlled Substances Act. This study assessed the potential for developing physical dep...

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Bibliographic Details
Main Authors: Robert H. Spencer, Catherine Munera, Megan J. Shram, Frédérique Menzaghi
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.13538